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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
26.36
Human Site:
Y880
Identified Species:
36.25
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
Y880
Q
R
T
G
I
L
L
Y
G
P
P
G
T
G
K
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
Y880
Q
R
T
G
I
L
L
Y
G
P
P
G
T
G
K
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
Y878
Q
R
T
G
I
L
L
Y
G
P
P
G
T
G
K
Dog
Lupus familis
XP_532459
1267
140567
Y864
Q
R
M
G
V
L
L
Y
G
P
P
G
T
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
Y881
Q
R
T
G
I
L
L
Y
G
P
P
G
T
G
K
Rat
Rattus norvegicus
P46462
806
89330
L420
A
L
C
S
E
A
A
L
Q
A
I
R
K
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
L782
Y
P
S
L
F
A
D
L
P
I
R
Q
R
M
G
Chicken
Gallus gallus
XP_418655
1290
143066
Y888
Q
R
S
G
V
L
L
Y
G
A
P
G
T
G
K
Frog
Xenopus laevis
P23787
805
89193
A419
A
A
L
C
S
E
A
A
L
Q
A
I
R
K
K
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
L420
A
L
C
S
E
A
A
L
Q
A
I
R
K
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
A415
L
A
S
L
C
S
E
A
A
L
Q
Q
I
R
E
Honey Bee
Apis mellifera
XP_397107
1069
120490
V683
G
N
K
T
E
G
W
V
F
Q
D
L
V
D
M
Nematode Worm
Caenorhab. elegans
P54812
810
89622
A424
A
S
L
C
S
E
A
A
I
Q
Q
I
R
E
K
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
Y1035
L
R
S
G
L
L
L
Y
G
P
P
G
T
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
E429
A
A
L
Q
C
I
R
E
K
M
D
V
I
D
L
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
Q657
E
K
I
F
Y
D
L
Q
L
E
R
D
C
D
N
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
H899
D
R
G
I
G
L
D
H
G
V
D
L
S
G
I
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
100
86.6
N.A.
100
0
N.A.
0
80
6.6
0
N.A.
0
0
6.6
80
P-Site Similarity:
100
100
100
93.3
N.A.
100
0
N.A.
6.6
93.3
6.6
0
N.A.
13.3
0
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
18
0
0
0
18
24
18
6
18
6
0
0
0
0
% A
% Cys:
0
0
12
12
12
0
0
0
0
0
0
0
6
0
0
% C
% Asp:
6
0
0
0
0
6
12
0
0
0
18
6
0
18
0
% D
% Glu:
6
0
0
0
18
12
6
6
0
6
0
0
0
6
6
% E
% Phe:
0
0
0
6
6
0
0
0
6
0
0
0
0
0
0
% F
% Gly:
6
0
6
42
6
6
0
0
48
0
0
42
0
48
6
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
6
24
6
0
0
6
6
12
12
12
0
6
% I
% Lys:
0
6
6
0
0
0
0
0
6
0
0
0
12
18
53
% K
% Leu:
12
12
18
12
6
48
48
18
12
6
0
12
0
0
6
% L
% Met:
0
0
6
0
0
0
0
0
0
6
0
0
0
6
18
% M
% Asn:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
6
% N
% Pro:
0
6
0
0
0
0
0
0
6
36
42
0
0
0
0
% P
% Gln:
36
0
0
6
0
0
0
6
12
18
12
12
0
0
0
% Q
% Arg:
0
48
0
0
0
0
6
0
0
0
12
12
18
6
0
% R
% Ser:
0
6
24
12
12
6
0
0
0
0
0
0
6
0
0
% S
% Thr:
0
0
24
6
0
0
0
0
0
0
0
0
42
0
0
% T
% Val:
0
0
0
0
12
0
0
6
0
6
0
6
6
0
0
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
6
0
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _